Izibulala-zinambuzane ze-biochemical ziyisibulala-zinambuzane esisemfashinini muva nje, futhi zidinga ukuhlangabezana nalezi zidingo ezimbili ezilandelayo.Enye iwukuthi ayinabo ubuthi obuqondile entweni yokulawula, kodwa inemiphumela ekhethekile kuphela njengokulawula ukukhula, ukuphazamisa ukukhwelana noma ukuheha;enye inhlanganisela yemvelo, uma ihlanganiswe ngokwenziwa, isakhiwo sayo kufanele sifane nesenhlanganisela yemvelo (umehluko wesilinganiso sama-isomers uvunyelwe).Ihlanganisa ikakhulukazi lezi zigaba ezilandelayo: amakhemikhali amakhemikhali, izilawuli zokukhula kwezitshalo zemvelo, izilawuli zokukhula kwezinambuzane zemvelo, izinqamuleli zezitshalo zemvelo, njll.

Izibulala-zinambuzane ezincane zibhekisela ezibulala-zinambuzane ezisebenzisa izinto eziphilayo ezifana namagciwane, isikhunta, amagciwane, i-protozoa noma ama-microorganisms ashintshwe izakhi njengezithako ezisebenzayo.NjengeBacillus, Streptomyces, Pseudomonas njalonjalo.

Izibulala-zinambuzane ze-botanical zibhekisela ezibulala-zinambuzane izithako zazo ezisebenzayo ezitholakala ngokuqondile ezitshalweni.Ezifana matrine, azadirachtin, rotenone, osthole nokunye.

Ama-antibiotic ezolimo abhekisela ezintweni zemvelo eziphilayo ezikhiqizwa inqubo yempilo ye-microbial engabonisa imiphumela ethize yezokwelapha kumagciwane ezitshalo ezindaweni eziphansi (ikakhulukazi ibhekisela emphumeleni wokuvimbela noma ukubulala amagciwane e-pathogenic).Okufana ne-avermectin, i-kasugamycin, i-spinosad, ivermectin, i-Jinggangmycin, njll.

Kodwa-ke, kufanele kuphawulwe ukuthi ama-antibiotic ezolimo akhiqizwa ukuvutshelwa kwe-microbial.Nakuba futhi kuyizibulala-zinambuzane zemvelo, ngokwezidingo zedatha yokubhaliswa, ngaphandle kwezinye izinto zokuhlola ezingakwazi ukuhlinzekwa ngenxa yezakhiwo ezikhethekile zomkhiqizo (ukunciphisa kungafakwa isicelo), ezinye ngokuyisisekelo zilingana nesibulala-zinambuzane samakhemikhali.Njengamanje, cishe awekho amanye amazwe emhlabeni ayiphatha njengesibulala-zinambuzane sezinto eziphilayo, kodwa ngokombono womthombo, ucwaningo kanye nesimo sokusetshenziswa, izibulala-zinambuzane ezibulala izinambuzane ziseyisigaba esibaluleke kakhulu sezibulala-zinambuzane zemvelo emlandweni wezwe lami futhi manje.